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Description

BUY SGT-78 ONLINE

SGT-78 (also known as CUMYL-CYBINACA or CUMYL-4CN-BINACA)is an indazole-3-carboxamide based cannabinoid  synthetic drugs that is  been sold online as a designer drug. While the in vitro activity of this compound isn’t unveiled in the related patent, anecdotal reports recommend it is a strong cannabinoid agonist with a functioning portion of around 0.1mg.

SGT-78 and all other synthetic cannabinoids sold on this site are proposed for research and legal applications. The exploration compound called SGT-78 is a creator drug with articulated physiological and psychoactive impacts and has the sub-atomic equation C22H24N4O. The recipe weight has the worth 360.5 g/mol.

The toxicological and physiological properties of SGT-78 are not known.
 Synthetic cannabinoids like SGT-78 may show high liking for fringe CB1 and CB2 cannabinoid receptors.

1-(4-cyanobutyl)- N-(1-methyl-1-phenylethyl)- 1H-indazole-3-carboxamide and all other originator drugs sold on this site are expected for research and measurable applications.

One examination led on SGT-78 portrayed the digestion just as the freedom of the exploration substance utilizing rodent and human liver microsomes alongside hepatocytes, which were utilized to contrast with pee inspecting and in vivo rodent plasma. The examination additionally analyzed hypothermia. The brooding with the microsomes demonstrated quick metabolic freedom notwithstanding, in the digestion in vivo took longer which permitted identification in the rodent plasma. The exploration synthetic demonstrated hypothermic impacts with 28 metabolites ready to be recognized.

Other examination shows that SGT-78 is an agonist at the receptors known as a cannabinoid. Being a simple of a comparable exacerbate the distinction noted was that a N-cumyl bunch supplanted the N-adamantyl gathering. For labs that wish to lead concentrates on SGT-78, it is essential to buy from an exploration synthetic maker that incorporates all information with respect to how to securely deal with the compound just as how to ensure the timeframe of realistic usability of the substance.

More examination should be directed in labs until information can be arranged to learn compound properties. As of now, a compound just expected for logical and criminological exploration and isn’t for human utilization.

Pharmaceutical kinetics:

SGT-78 is a synthetic cannabinoid that is also known as CYMYL-4CN-BINACA and CUMYL-CYBINACA. formally named 1-(4-cyanobutyl)-N-(1-methyl-1-phenylethyl)-1H-indazole-3-carboxamide (C22H24N4O) [1]. The physiological and psychoactive effects of SGT-78 are highly evident. Studies have shown that it has a high affinity for binding to cannabinoid receptors CB1 and CB2, but it prefers CB1 receptors. A comparison of SGT-78 with its closely related compound SGT-25 (5F-CUMYL-PINACA) shows that it has a better affinity for cannabinoid receptors.

Research Studies of SGT-78:

Studying the effects of SGT-78 on mice was the focus of a 2019 publication in Frontiers in Pharmacology. Their research shows that it has convulsant effects and causes a hypothermic reaction because it tightly binds to CB1 receptors. The researchers noted that these effects occurred at a lower dose than previously reported for any synthetic cannabinoid, suggesting it has a high potency within the endocannabinoid system.

Another study, published in 2018 in “Drug Test Analysis,” found that when the body metabolizes , it produces the deadly toxin cyanide as a byproduct .

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