Butylone (BK-MBDB)

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Butylone (Bk-MBDB). talking about Butylone, also known as β-keto-N-methylbenzodioxolylbutanamine is an entactogen, psychedelic, and stimulant psychoactive drug of the phenethylamine chemical class.

The most common metabolite is the 4-OH-3-MeO metabolite. The metabolites containing a hydroxyl-group would be excreted as their conjugates in urine

Butylone is being sold online at drharrisonclinic.com and has a full IUPAC name of 1-(1,3-benzodioxol-5-yl)-2-(methylamino)-1-butanone, monohydrochloride which belongs to a class of research chemicals called central nervous system stimulants.

There are three major metabolic pathways of bk-MBDB as shown in the figure. As result of demethylation followed by O-methylation Butylone (BK-MBDB) metabolizes into 4-OH-3-MeO and 3-OH-4-MeO metabolites in human urine. The second pathway is a β-ketone reduction into β-ketone reduced metabolites. The third pathway is an N-dealkylation into N-dealkylmetabolites.

As with MDMA and Methylone, Butylone operates in a similar manner to increase extracellular monoamine levels. Koeppe, Ludwig and Zeile describe synthesizing Butylone in their 1967 paper. Until 2005, butylone was an obscure product of academia, but it was later acquired by a manufacturer of designer drugs. Butylone has the same relationship to MBDB as MDMA (“Ecstasy”) has to methylone. Formal research on this chemical was first conducted in 2009, when it was shown to be metabolised in a similar manner to related drugs like methylone Butylone, also known as β-keto-N-methyl benzodioxol yl butanamide (βk-MBDB), is an entactogen, psychedelic, and stimulant psychoactive drug of the phenethylamine chemical class. It is the β-keto (substitute cathinone) analogue of MBDB and the substitute methylenedioxyphenethylamine analogue of buphedrone.

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